Semester VII · PCI syllabus 2026
Precision Medicine
BP708T-E7
1 credit
Elective
Coming soon
Unit 1: Unit 1
- Introduction to Precision Medicine and Its Relevance to Pharmacy Definition and scope of precision medicine Evolution from “one-size-fits-all” to personalized approaches Key components: genomics, epigenetics, environmental factors, lifestyle
Unit 2: Unit 2
- Role of pharmacists in precision medicine Interdisciplinary nature (clinicians, bioinformaticians, pharmacologists) Pharmacogenomics in Drug Response and Safety Basic human genetics relevant to pharmacy Genotype-phenotype relationships Genetic polymorphisms: CYP450 enzymes (CYP2D6, CYP2C9, etc.)
Unit 3: Unit 3
- FDA drug labelling and pharmacogenomic biomarkers Tools/databases: AlphaGenome, PharmGKB, CPIC, SNPedia Biomarkers, Targeted Therapy, and Companion Diagnostics Types of biomarkers: predictive, prognostic, diagnostic Role of biomarkers in targeted therapy Companion diagnostics: regulatory approval and clinical application Case study: Trastuzumab and HER2 testing in breast cancer
Unit 4: Unit 4
- Lab-on-chip and biosensor technologies Targeted nano-delivery in oncology Antibody-drug conjugates (ADCs) Smart delivery systems (stimuli-responsive biosensors) Technology, AI, and Big Data in Precision Medicine Role of AI, machine learning, and data analytics in precision medicine Electronic Health Records (EHRs), clinical decision support systems
Unit 5: Unit 5
- Integration of genomic data with patient profiles Examples of AI-driven drug discovery Data security and interoperability Regulatory, Ethical, and Clinical Implementation Regulatory guidelines (US FDA, EMA, CDSCO) for genomic-based therapies Clinical trial design for precision drugs
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