Heterocyclic Compounds and Stereochemistry (Practical)

List of Practicals

1. 12 experiments must be performed)
2. Prepare, purify and characterize melting point, recrystallization following compounds (Minimum of 04 aromatic and any two heterocyclic compounds different chemical reactions) a. Benzanilide/phenyl benzoate/acetanilide from aniline/ phenol by acetylation/acylation reaction. b. 2,4,6-Tribromo aniline from aniline/para bromo acetanilide from Acetanilide halogenation (Bromination) reaction. c. 5-Nitro salicylic acid f r o m salicylic acid / meta di-nitro benzene from by nitration reaction. reaction. e. 1-Phenyl-azo-2-napthol from aniline by diazotization and coupling reactions. f. Synthesis of 2,4,6- trinitrophenol by nitration reaction g. Synthesis of 3,5-dimethyl pyrazole from acetylacetone. h. Synthesis of benzimidazole from ortho phenylene diamine i. Preparation of benzophenone oxime.
3. Qualitative analysis of binary mixture of organic compounds (any two) (Acid and Base + Neutral).
4. To draw and visualize 3D structures, calculate molecular properties Chemical reactions using software tools