Analytical Method Development and Validation

List of Practicals

1. Development of a UV-Visible spectrophotometric method for the assay of paracetamol API. Construction of calibration curve for a model API using spectrophotometry.
2. Determination of solid dosage form by using dissolution method.
3. Analytical method development and validation of Atenolol/metformin by HPLC.
4. Investigation of different columns for HPLC separation of a Multi-component Mixture.
5. Optimization of mobile Phase composition for HPLC analysis of a selected
6. Optimization of Flow rate and temperature in HPLC for paracetamol/ caffeine.
7. Selection of wavelength for spectrophotometric analysis by HPLC of Marketed
8. Determination of λmax and calibration curve for qualitative analysis of paracetamol.
9. Determination of effect of pH on Retention time in RP-HPLC.
10. Validation of HPLC method : Determination of LOD and LOQ for paracetamol HPLC
11. Preliminary Investigation of forced Degradation studies on Ibuprofen by
12. Method development for related substances of a drug substance using HPLC.
13. Determination of residual solvent analysis for ethanol/acetone in API by Chromatography.
14. Development of titrimetric method for the assay of marketed drugs(Ascorbic acid/sodium bicarbonate).