Biopharmaceutics and Pharmacokinetics (Practical)

List of Practicals

1. To calculate MRT from the given data.
2. To assess the effect of protein binding of a drug
3. To report relative bioavailability of given drug product using urinary excretion
4. To report relative bioavailability of given drug product using plasma data
5. Establish IVIVC from the given in vitro and in vivo data.
6. To calculate pharmacokinetic parameters of a drug using given plasma level
7. To report bioequivalence of drug products using given urinary excretion administered
8. To calculate absorption rate constant, elimination rate constant and elimination life of given excretion data by sigma minus method.
9. To calculate absorption rate constant, elimination rate constant and elimination life of the given drug data administered by IV bolus injection represented compartment model.
10. To calculate the absorption rate constant by using curve fitting method.
11. To calculate various pharmacokinetic parameters using in silico methods. recommended software’s shall be used for performing experiments.