Biomedicinal Chemistry (Practical)

List of Practicals

1. Preparation of Drugs / Intermediates (Any 4) • 7-Hydroxy-4-methyl coumarin • Thiobarbituric acid • 2,3-Diphenylquinoxaline • Sulphanilamide • Triphenyl imidazole • Perform synthesis of intermediate/drug using microwave irradiation chemistry techniques.
2. Assay of Drugs (Any 4) • Sulpha drugs • Metronidazole • Isoniazid • Phenobarbitone • Benzyl penicillin • Chloroquine
3. Drug Design & Computational Tools (Any 4) • Calculate physicochemical and ADME properties using Swiss ADME (e.g. logP, molecular weight, H-bond donors/acceptors) • Perform basic molecular docking studies using any of open-source academic tools.