Semester IV · PCI syllabus 2026
Pharmaceutical Biotechnology
BP403T
3 credits
Theory
Coming soon
Unit 1: Introduction to Pharmaceutical Biotechnology
- therapeutics; analytical characterization of proteins; monoclonal antibodies; antigens; enzyme immobilization; cell culture and immobilization techniques; pharmaceutical applications
Unit 2: Genetic Engineering and Recombinant DNA Technology
- Principles of genetic engineering; recombinant DNA technology; production of interferons, hepatitis-B vaccine, and insulin; polymerase chain reaction (PCR) and its applications; mutations and types of mutants
Unit 3: Microbial Biotransformation and Fermentation Technology
- Microbial biotransformation; fermentation principles and process control; industrial production of alcohol, penicillins, citric acid, and vitamin B₁₂; blood products—collection, processing, and storage
Unit 4: Gene Therapy, Genomics and Personalized Medicine
- Gene therapy—types and methodologies; delivery systems; ethical concerns and challenges; Human Genome Project; role of bioinformatics and artificial intelligence in personalized medicine
Unit 5: Immunology, Vaccines and Sera
- Basics of immunology; types and generations of vaccines; immunization strategies; vaccine preparation, evaluation, and standardization; regulatory aspects; sera therapy; marketed products; challenges and newer approaches
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